| DDAH1 |
| LOCUS ID | 23576 | ||||
| GENE_SYMBOL | DDAH1 | ||||
| GENE NAME | dimethylarginine dimethylaminohydrolase 1 | ||||
| SYNONYMNS | DDAH, HEL-S-16 | ||||
| CHROMOSOME | 1 | ||||
| HOMOLOGENE ID | 8120 | ||||
| SOURCE | RAT |
| PMIDs | 19748504 |
| GENE SUMMARY |
|---|
| This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. [provided by RefSeq, Jul 2008] |
| OBSERVATION |
|---|
| 1. It can be concluded that PRMT-I and DDAHs-induced upregulation of ADMA levels might be involved in ROS- and RAS-mediated diabetic retinopathy. |