| ANXA5 |
| LOCUS ID | 308 | ||||||||||
| GENE_SYMBOL | ANXA5 | ||||||||||
| GENE NAME | annexin A5 | ||||||||||
| SYNONYMNS | PP4,ANX5,ENX2,RPRGL3,HEL-S-7 | ||||||||||
| CHROMOSOME | 4 | ||||||||||
| HOMOLOGENE ID | 20312 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular an |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Cardiovascular | 1. CONCLUSION: Circulating anxA5 levels are associated with carotid intima-media thickness but not coronary plaque composition in high-risk patients with diabetes mellitus | 28592134 |