| CDC123 |
| LOCUS ID | 8872 | ||||||||||
| GENE_SYMBOL | CDC123 | ||||||||||
| GENE NAME | cell division cycle | ||||||||||
| SYNONYMNS | D123, C10orf7 | ||||||||||
| CHROMOSOME | 10 | ||||||||||
| HOMOLOGENE ID | 4394 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and is involved with metabolic and hormol processes. Mutations in this gene are associated with adiponectin deficiency. Multiple altertively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Apr 2010] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Cardiovascular | 1. Variants in WFS1, CDKN2A/B, KCNJ11, CDC123/CAMK1D, JAZF1, SLC30A8, FTO, CDKAL1, and HHEX/IDE genes are significantly associated with T2DM in She Chinese subjects. JAZF1, FTO, CDKAL1, and HHEX/IDE are associated with diabetic nephropathy. WFS1, CDKN2A/B, CDC123/CAMK1D, JAZF1, FTO, CDKAL1, and HHEX/IDE are associated with cardiovascular risk | 23298195 |