| FKBP8 |
| LOCUS ID | 23770 | ||||||||||
| GENE_SYMBOL | FKBP8 | ||||||||||
| GENE NAME | FK506 binding protei | ||||||||||
| SYNONYMNS | FKBP38, FKBPr38 | ||||||||||
| CHROMOSOME | 19 | ||||||||||
| HOMOLOGENE ID | 7720 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. Unlike the other members of the family, this encoded protein does not seem to have PPIase/rotamase activity. It may have a role in neurons associated with memory function. [provided by RefSeq, Jul 2008] |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Cardiovascular | 1. Many individual genes within the PPIase family are associated with several age-related diseases including cardiovascular diseases (CVDs), atherosclerosis, type II diabetes (T2D), chronic kidney disease (CDK), neurodegeneration, cancer and age-related macular degeneration (AMD), in addition to the ageing process itself. | 25986561 |