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FZD5 |
LOCUS ID | 7855 | ||||||||||
GENE_SYMBOL | FZD5 | ||||||||||
GENE NAME | frizzled class recep | ||||||||||
SYNONYMNS | HFZ5 C2orf31 | ||||||||||
CHROMOSOME | 2 | ||||||||||
HOMOLOGENE ID | 2590 |
microRNAs | NA | NA |
GENE SUMMARY |
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Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand. [provided by RefSeq, Jul 2008] |
OBSERVATIONS |
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Complication | Evidence | PMID |
Cardiovascular | 1. CONCLUSION: MicroRNA-216b was overexposed in diabetic MMECs and its downregulation may actively enhance angiogenesis in diabetic angiopathy through inverse regulation on FZD5. | 29477872 |