| PRDX2 |
| LOCUS ID | 7001 | ||||||||||
| GENE_SYMBOL | PRDX2 | ||||||||||
| GENE NAME | peroxiredoxin 2 | ||||||||||
| SYNONYMNS | PRP, TSA, PRX2, PTX1, TPX1, NKEFB, PRXII, TDPX1, NKEF-B, HEL-S-2a | ||||||||||
| CHROMOSOME | 19 | ||||||||||
| HOMOLOGENE ID | 21182 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolyt |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Cardiovascular | 1. In , PRDX1, -2, -4, and -6 showed differential correlations with a variety of traditional cardiovascular risk factors. | 25742636 |