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PRDX6 |
LOCUS ID | 9588 | ||||||||||
GENE_SYMBOL | PRDX6 | ||||||||||
GENE NAME | peroxiredoxin 6 | ||||||||||
SYNONYMNS | PRX, p29, AOP2, 1-Cys, NSGPx, aiPLA2, HEL-S-128m | ||||||||||
CHROMOSOME | 1 | ||||||||||
HOMOLOGENE ID | 3606 |
microRNAs | NA | NA |
GENE SUMMARY |
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The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008] |
OBSERVATIONS |
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Complication | Evidence | PMID |
Cardiovascular | 1. In , PRDX1, -2, -4, and -6 showed differential correlations with a variety of traditional cardiovascular risk factors. | 25742636 |