PRDX6
LOCUS ID9588
GENE_SYMBOLPRDX6
GENE NAMEperoxiredoxin 6
SYNONYMNSPRX, p29, AOP2, 1-Cys, NSGPx, aiPLA2, HEL-S-128m
CHROMOSOME1
HOMOLOGENE ID3606
microRNAsNANA
GENE SUMMARY
The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]

OBSERVATIONS

Complication Evidence PMID
Cardiovascular1. In , PRDX1, -2, -4, and -6 showed differential correlations with a variety of traditional cardiovascular risk factors.25742636