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PRMT2 |
LOCUS ID | 3275 | ||||||||||
GENE_SYMBOL | PRMT2 | ||||||||||
GENE NAME | protein arginine met | ||||||||||
SYNONYMNS | HRMT1L1 | ||||||||||
CHROMOSOME | 21 | ||||||||||
HOMOLOGENE ID | 55587 |
microRNAs | NA | NA |
GENE SUMMARY |
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PRMT2 (Protein Arginine Methyltransferase 2) is a Protein Coding gene. Diseases associated with PRMT2 include Breast Cancer. Among its related pathways are Retinoblastoma (RB) in Cancer and mRNA Splicing - Major Pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and transcription coactivator activity. An important paralog of this gene is CARM1. |
OBSERVATIONS |
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Complication | Evidence | PMID |
Atherosclerosis | 1. Thus, PRMT2 represents a glucose-sensitive factor that plays a role in LXR-mediated ABCA1-dependent cholesterol efflux and lends insight to the presence of increased atherosclerosis in diabetic patients. | 26288135 |