Differentially Expressed Genes with P-Value < 5%.
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| Gene |
P-value |
Adjst. P-Value |
LogFC |
| ABCA1 | 0.040762461 | 0.446535352 | -0.100844792 |
| ABCG1 | 0.035528746 | 0.432289807 | -0.178963287 |
| ADAMTS13 | 0.024196127 | 0.398347012 | 0.055130797 |
| AGTR1 | 0.049217321 | 0.469253768 | -0.118096518 |
| AOC3 | 0.037771398 | 0.438644125 | -0.242462634 |
| API5 | 0.03266357 | 0.423881308 | -0.080379538 |
| ATM | 0.032642254 | 0.423866013 | -0.042508666 |
| CACNA1H | 0.037072029 | 0.437895144 | 0.050888298 |
| CD47 | 0.026900083 | 0.405601615 | -0.067138388 |
| CD69 | 0.015034235 | 0.351768328 | -0.050635767 |
| CDK7 | 0.021292058 | 0.386692431 | -0.123058109 |
| CDKAL1 | 0.034146629 | 0.42905887 | -0.093542968 |
| CHIT1 | 0.025970304 | 0.40126478 | 0.052028451 |
| CLCN5 | 0.002033918 | 0.199683751 | -0.043978122 |
| DCXR | 0.029842685 | 0.414644121 | -0.227874136 |
| DDIT3 | 0.047483562 | 0.465299634 | -0.100701158 |
| ELN | 0.043418595 | 0.453557326 | 0.041828719 |
| ENG | 0.010730031 | 0.325203749 | 0.101189419 |
| EXOSC7 | 0.000599895 | 0.143206695 | -0.124391012 |
| F11 | 0.010743405 | 0.325203749 | -0.041627654 |
| FABP4 | 0.023155776 | 0.396587408 | -0.308020786 |
| FADS1 | 0.035077257 | 0.43076765 | -0.053799585 |
| FFAR1 | 0.039403465 | 0.440175475 | 0.034590995 |
| FKBP2 | 0.010939468 | 0.326490687 | -0.128753166 |
| FMOD | 0.042062601 | 0.451186556 | -0.094098985 |
| GK | 0.014577624 | 0.350279013 | -0.045755083 |
| GNB3 | 0.038502034 | 0.438644125 | 0.065519441 |
| HRH2 | 0.023434988 | 0.39688958 | 0.069889962 |
| IFNG | 0.029084284 | 0.41049941 | 0.04567303 |
| IGF1 | 0.022575939 | 0.393378263 | -0.111740986 |
| IL10 | 0.004216703 | 0.244121947 | -0.054163265 |
| ITGB3 | 0.029733176 | 0.414644121 | 0.026000065 |
| LIMK2 | 0.028677323 | 0.41031303 | 0.037592469 |
| LPL | 0.000924739 | 0.154762389 | -0.377082956 |
| MAP3K5 | 0.024127759 | 0.398347012 | -0.11874721 |
| MIF | 0.026456258 | 0.403604778 | -0.214518999 |
| NGB | 0.03597906 | 0.434307926 | 0.049416892 |
| NQO1 | 0.032838498 | 0.425103038 | -0.113605854 |
| NTS | 0.028361381 | 0.409153303 | -0.058184177 |
| ONECUT1 | 0.010082359 | 0.316751612 | 0.075286275 |
| P2RX3 | 0.001035188 | 0.155160118 | 0.105154007 |
| PLIN1 | 0.04226106 | 0.452238464 | -0.264148638 |
| RGN | 0.009747795 | 0.31489632 | -0.162674693 |
| SFI1 | 0.000453051 | 0.141554935 | 0.067872945 |
| SLC2A2 | 0.037970873 | 0.438644125 | -0.044914079 |
| SLC2A4 | 0.032292096 | 0.421398839 | -0.105805354 |
| SOCS2 | 0.00424479 | 0.244121947 | -0.15421351 |
| SOX9 | 0.046985412 | 0.463549291 | 0.073551524 |
| SRGN | 0.03977792 | 0.441140906 | -0.103423583 |
| STH | 0.018507542 | 0.37800138 | 0.101138155 |
| TFAM | 0.006556402 | 0.279167065 | -0.106488683 |
| TIMP1 | 0.036715419 | 0.437455791 | -0.152883712 |
| TNFRSF1B | 0.01293069 | 0.337369165 | 0.091260854 |
| TRPV4 | 0.004950725 | 0.256038851 | 0.092745346 |
| TXN | 0.002184677 | 0.199719047 | -0.13717311 |
| WT1 | 0.015009912 | 0.351768328 | -0.037666471 |
GSE25462: Increased SRF Transcriptional Activity is a Novel Signature of Insulin Resistance in Humans and Mice.
Samples: 15 Normoglycemic individuals without diabetes in any first-degree relative, 25 normoglycemic individuals with 1 or both parents with T2D and 10 drug-naive individuals with established T2D
