PSIP1
LOCUS ID11168
GENE_SYMBOLPSIP1
GENE NAMEPC4 and SFRS1 interacting protein 1
SYNONYMNSp52, p75, PAIP, DFS70, LEDGF, PSIP2
CHROMOSOME9
HOMOLOGENE ID13242
DiseaseDiabetic Retinopathy
PMIDs23918145
GENE SUMMARY
PSIP1 (PC4 And SFRS1 Interacting Protein 1) is a Protein Coding gene. Diseases associated with PSIP1 include?Hiv-1. Among its related pathways are?Activation of cAMP-Dependent PKA?and?GPCR Pathway. GO annotations related to this gene include?poly(A) RNA binding?and?RNA polymerase II transcription coactivator activity. An important paralog of this gene is?HDGFRP2.

OBSERVATIONS
1. These findings underscore the importance of p75(NTR) as a novel regulator of inflammation and potential therapeutic target in diabetic retinopathy