SLC5A2
LOCUS ID6524
GENE_SYMBOLSLC5A2
GENE NAMEsolute carrier family 5 (sodium/glucose cotransporter), member 2
SYNONYMNSSGLT2
CHROMOSOME16
HOMOLOGENE ID2289
DiseaseType 2 diabetes
PMIDs25352807
GENE SUMMARY
This gene encodes a member of the sodium glucose cotransporter family which are sodium-dependent glucose transport proteins. The encoded protein is the major cotransporter involved in glucose reabsorption in the kidney. Mutations in this gene are associated with renal glucosuria. Two transcript variants, one protein-coding and one not, have been found for this gene. [provided by RefSeq, Feb 2015]

OBSERVATIONS
The Renal sodium-dependent glucose co-transporter 2 (SGLT2) is one of the most promising targets for the treatment of type 2 diabetes