CDKAL1
LOCUS ID54901
GENE_SYMBOLCDKAL1
GENE NAMECDK5 regulatory subunit associated protein 1-like 1
SYNONYMNSNA
CHROMOSOME6
HOMOLOGENE ID9830
microRNAsNANA
GENE SUMMARY
The protein encoded by this gene is a member of the methylthiotransferase family. The function of this gene is not known. Genome-wide association studies have linked single nucleotide polymorphisms in an intron of this gene with susceptibilty to type 2 diabetes. [provided by RefSeq, May 2010]

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. JAZF1, FTO, CDKAL1, and HHEX/IDE are associated with diabetic nephropathy.23298195
Cardiovascular1. WFS1, CDKN2A/B, CDC123/CAMK1D, JAZF1, FTO, CDKAL1, and HHEX/IDE are associated with cardiovascular risk.23298195
Retinopathy1. CDKAL1 rs7756992 is associated with diabetic retinopathy in a Chinese population with type 2 diabetes.28821857