FN3K
LOCUS ID64122
GENE_SYMBOLFN3K
GENE NAMEfructosamine 3 kinase
SYNONYMNSNONE
CHROMOSOME17
HOMOLOGENE ID23336
microRNAsNANA
GENE SUMMARY
A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way, fructosamines, are less active or functiol. This gene encodes an enzyme which catalyzes the phosphorylation of fructosamines which may result in deglycation. [provided by RefSeq, Feb 2012]

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. We found combined effect of TKT SNP rs11130362 and FN3K SNP rs1056534 on DN progression (p<0.01).23492569