GFPT1
LOCUS ID2673
GENE_SYMBOLGFPT1
GENE NAMEglutamine--fructose-6-phosphate transamise 1
SYNONYMNSGFA, GFAT, GFPT, MSLG, CMS12, GFAT1, CMSTA1, GFAT, 1, GFAT1m, GFPT1L
CHROMOSOME2
HOMOLOGENE ID68220
microRNAsNANA
GENE SUMMARY
This gene encodes the first and rate-limiting enzyme of the hexosamine pathway and controls the flux of glucose into the hexosamine pathway. The product of this gene catalyzes the formation of glucosamine 6-phosphate. [provided by RefSeq, Sep 2008]

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. Genetic variation in GFPT1 is thus unlikely to have a major impact on susceptibility to diabetic nephropathy.14988277