HCN2
LOCUS ID610
GENE_SYMBOLHCN2
GENE NAMEhyperpolarization activated cyclic nucleotide gated potassium channel 2
SYNONYMNSBCNG2, HAC-1, BCNG-2
CHROMOSOME19
HOMOLOGENE ID31022
microRNAsNANA
GENE SUMMARY
Hyperpolarization-activated cation channels of the HCN gene family, such as HCN2, contribute to spontaneous rhythmic activity in both heart and brain.[supplied by OMIM, Jul 2010]

OBSERVATIONS

Complication Evidence PMID
Neuropathy1. These indicate that diabetes induces the overexpression of HCN channels and the electrophysiological changes of HCN currents in the A- and C-fiber nodose neurons, which might contribute to the diabetes-induced alteration of cell excitability in the vagal afferent neurons.19815055