HSPA5
LOCUS ID3309
GENE_SYMBOLHSPA5
GENE NAMEheat shock protein family A (Hsp70) member 5
SYNONYMNSBIP, MIF2, GRP78, HEL-S-89n
CHROMOSOME9
HOMOLOGENE ID3908
microRNAsNANA
GENE SUMMARY
The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.[provided by RefSeq, Sep 2010]

OBSERVATIONS

Complication Evidence PMID
Neuropathy1. Our study suggested that the GRP78 rs391957 promoter polymorphism is a potential risk factor for type 2 diabetic peripheral neuropathy.26005757