| LAMP1 |
| LOCUS ID | 3916 | ||||||||||
| GENE_SYMBOL | LAMP1 | ||||||||||
| GENE NAME | lysosomal associated | ||||||||||
| SYNONYMNS | LAMPA, CD107a, LGP120 | ||||||||||
| CHROMOSOME | 13 | ||||||||||
| HOMOLOGENE ID | 4061 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Tuberculosis | 1. CD8(+) T cells were associated with significantly diminished expression of the cytotoxic markers perforin, granzyme B and CD107a both at baseline and following antigen or anti-CD3 stimulation, while NK cells were associated with significantly decreased antigen-stimulated expression of CD107a only. | 25363329 |