POLR2D
LOCUS ID5433
GENE_SYMBOLPOLR2D
GENE NAMEpolymerase (R) II (D directed) polypeptide D
SYNONYMNSRBP4, RPB16, HSRBP4, HSRPB4
CHROMOSOME2
HOMOLOGENE ID37968
microRNAsNANA
GENE SUMMARY
This gene encodes the fourth largest subunit of R polymerase II, the polymerase responsible for synthesizing messenger R in eukaryotes. In yeast, this polymerase subunit is associated with the polymerase under suboptimal growth conditions and may have a stress protective role. A sequence for a ribosomal pseudogene is contained within the 3' untranslated region of the transcript from this gene. [provided by RefSeq, Jul 2008]

OBSERVATIONS

Complication Evidence PMID
Retinopathy1. RBP4 may be involved in the process of diabetic retinopathy and may be a novel biomarker for its diagnosis and treatment in diabetic patients.20233518