PTX3
LOCUS ID5806
GENE_SYMBOLPTX3
GENE NAMEpentraxin 3, long
SYNONYMNSTSG-14, TNFAIP5
CHROMOSOME3
HOMOLOGENE ID7500
microRNAsNANA
GENE SUMMARY
NA

OBSERVATIONS

Complication Evidence PMID
Nephropathy1. The current study provided the first evidence that decreased plasma PTX3 levels are associated with T2DM and DN in Malay men and also suggested that PTX3 may have different effects in DN and chronic kidney diseases. 2. Our findings suggested that PTX3 polymorphisms were associated with an increased risk for DN in Chinese patients with type 2 diabetes.24350299, 28119515
Retinopathy1. Plasma PTX3 is positively associated with DR development and progression, and may be a more accurate predictor of DR development than hsCRP.25159210
Atherosclerosis1. It is well known that inflammatory biomarkers [high-sensitivity C-reactive protein (hs-CRP), pentraxin3 (PTX3)] and oxidative stress markers [malondialdehyde low-density lipoprotein (MDA-LDL)] are associated with atherosclerotic changes.26162942