A Gene Atlas of Type 2 Diabetes Mellitus Associated Complex Disorders
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Gene | P-value | Adjst. P-Value | LogFC |
---|---|---|---|
ABCA1 | 0.012207722 | 0.117134812 | -30.56683055 |
ABCG1 | 0.000297453 | 0.025197374 | -0.858226575 |
ACVRL1 | 0.021538821 | 0.138818455 | -7.173120609 |
ADCYAP1 | 0.0275032 | 0.14959906 | -0.333322853 |
ADH1B | 0.028982476 | 0.152005443 | -28.52121952 |
ADIPOQ | 0.021136418 | 0.138086506 | -17.71666502 |
ADK | 0.000566293 | 0.033778737 | -1.127246093 |
ADM | 0.026725923 | 0.147812744 | -25.75798153 |
AGTR1 | 0.033373394 | 0.162030342 | -3.278306689 |
AKR1B10 | 0.005970594 | 0.090545013 | 7.663142366 |
AKT1 | 0.016757977 | 0.129250138 | -14.85284477 |
ALDH2 | 0.012995738 | 0.119067655 | -156.9459635 |
ALOX5AP | 0.036499105 | 0.169143668 | -10.32824186 |
ALPK1 | 0.043561775 | 0.186667662 | -1.496196985 |
AMBP | 0.038633881 | 0.174035777 | 0.348024869 |
ANG | 0.014576728 | 0.123179616 | -29.62872806 |
ANGPT2 | 0.005411536 | 0.087837561 | -4.614271797 |
ANGPTL2 | 4.96E-06 | 0.002188997 | -78.3264746 |
AOC3 | 0.015848809 | 0.126704857 | -3.337043678 |
API5 | 0.04601333 | 0.191695541 | -4.810898149 |
APOC1 | 0.004377295 | 0.081039035 | -4.270499553 |
APOE | 0.019620228 | 0.135425325 | -74.50513458 |
AQP1 | 0.008894643 | 0.104797103 | -8.914375045 |
AQP5 | 0.013850334 | 0.121063505 | -0.358389611 |
AR | 0.012876326 | 0.118752006 | -0.782978761 |
ATM | 0.008780515 | 0.104315293 | -2.862151071 |
ATP2A2 | 0.02993789 | 0.154087196 | 275.5327075 |
B2M | 0.034007394 | 0.163602676 | -69.90649532 |
BASP1 | 0.000913685 | 0.043372447 | -10.55324909 |
BCL2 | 0.018938006 | 0.134545928 | -3.434291174 |
BMP2 | 0.013423102 | 0.120267746 | -2.496965438 |
BMP4 | 0.024193327 | 0.143053898 | -1.199869745 |
C5 | 0.014234896 | 0.122055034 | -4.027243131 |
CACNA1H | 0.00125092 | 0.0494367 | -1.837222818 |
CAPN10 | 0.036204226 | 0.168490956 | -0.124229884 |
CAT | 0.031808614 | 0.158187965 | -46.25541078 |
CAV1 | 0.021341771 | 0.138488627 | -119.6752496 |
CCL5 | 0.024392052 | 0.143187136 | -26.0474666 |
CCR1 | 0.02185206 | 0.139156511 | -0.464493118 |
CD247 | 0.024323527 | 0.143053898 | -9.229628288 |
CD34 | 0.003782725 | 0.077124542 | -25.73403905 |
CD47 | 0.014483728 | 0.122940662 | -3.394511297 |
CD59 | 0.021981553 | 0.139398317 | -3.083860722 |
CD63 | 0.014144425 | 0.121828 | -6.691806999 |
CD74 | 0.032106092 | 0.158780502 | -46.20758968 |
CD9 | 0.000111325 | 0.014628629 | -1.507344372 |
CDC123 | 0.004072052 | 0.07898902 | -7.109552068 |
CETP | 0.028570782 | 0.15116978 | -1.706772375 |
CHPT1 | 0.002948439 | 0.070724726 | -8.554091099 |
CLEC11A | 0.003802917 | 0.077283998 | -1.33314002 |
CNDP2 | 0.04073295 | 0.179117994 | -27.28405608 |
CNTF | 0.019113223 | 0.134821035 | -0.207336399 |
COL8A1 | 0.003921134 | 0.078087581 | -3.583316071 |
COL8A2 | 1.39E-06 | 0.000873698 | -1.495581295 |
COLEC12 | 0.000381542 | 0.029176972 | -4.410635693 |
CRH | 0.020688736 | 0.13749012 | -0.556369318 |
CRK | 0.030381345 | 0.155074916 | -8.274920418 |
CTGF | 0.015648056 | 0.126009615 | -11.72735223 |
CTSH | 0.04163392 | 0.181788926 | -14.07752242 |
CUBN | 0.026342556 | 0.14720941 | -0.962479658 |
CXCL12 | 0.002398672 | 0.066446967 | -22.56159419 |
CXCL16 | 0.029467365 | 0.152954286 | -2.780388235 |
CYBA | 0.009018199 | 0.105487473 | -17.16412121 |
CYP2J2 | 0.021094812 | 0.138046005 | 23.22282271 |
CYR61 | 0.016445016 | 0.12837113 | 29.0813835 |
DHCR7 | 0.043567412 | 0.186667662 | -3.851343556 |
DNMT1 | 0.011798929 | 0.115464012 | -10.53293278 |
EBF1 | 0.015805917 | 0.126603334 | -34.24179927 |
EBF2 | 0.011158967 | 0.113342125 | -2.17762105 |
EDN1 | 0.012193242 | 0.117084455 | -2.574507072 |
EDNRA | 0.014003514 | 0.121362178 | -4.566640349 |
EGF | 0.002608412 | 0.067590734 | 1.045533692 |
EGFR | 0.024110653 | 0.142850981 | -0.93128015 |
ELMO1 | 0.027636406 | 0.149914691 | -1.874042966 |
ELN | 0.001475398 | 0.053693997 | -0.803694616 |
ENG | 0.015746271 | 0.126407288 | -25.51864153 |
ENG | 0.015746271 | 0.126407288 | -25.51864153 |
ENPP2 | 0.018233679 | 0.133238781 | -35.78238938 |
ENTPD1 | 0.008231261 | 0.102115534 | -1.339187754 |
EPOR | 0.037161899 | 0.170737075 | -0.688342711 |
ERRFI1 | 0.014674722 | 0.123207242 | -6.152849892 |
ESAM | 0.029351396 | 0.15277558 | -30.18232094 |
F2R | 0.045577317 | 0.190890582 | 78.78585229 |
FABP4 | 0.029178699 | 0.152399188 | -48.56639579 |
FABP5 | 0.028937612 | 0.151928499 | -25.50104621 |
FADS1 | 0.018189473 | 0.133096125 | -17.15514622 |
FADS2 | 0.008852378 | 0.104565744 | -1.348062087 |
FASN | 0.013293323 | 0.119930002 | -270.1105402 |
FBXO8 | 0.011527794 | 0.114573188 | -3.932914902 |
FFAR2 | 0.027720148 | 0.150058447 | -1.073816145 |
FGFR1 | 0.00352933 | 0.076033624 | -0.464656284 |
FMO3 | 0.011189343 | 0.113513174 | -1.242393613 |
FMOD | 0.008416298 | 0.102673935 | -23.59579256 |
FPR1 | 0.044180033 | 0.187884629 | -3.981651779 |
FRMD3 | 0.015890814 | 0.126732056 | -9.656114397 |
G6PD | 0.024066594 | 0.142804583 | -4.554973434 |
GAS1 | 5.60E-07 | 0.000440556 | -18.00700132 |
GFPT2 | 0.001276317 | 0.050082982 | -2.80091854 |
GHR | 0.039814563 | 0.176915331 | -12.40581602 |
GPX1 | 0.025425533 | 0.145540925 | -49.95492483 |
GSTM1 | 0.003674786 | 0.076345114 | 54.62967947 |
HBG2 | 0.040600423 | 0.17897659 | 7.795145961 |
HHEX | 0.001982387 | 0.061333233 | -1.053602086 |
HLA-A | 0.022008439 | 0.139398317 | -129.9674084 |
HLA-DQA1 | 0.030429794 | 0.155114645 | -13.17724284 |
HMGCS2 | 0.002625221 | 0.067590734 | 7.103416209 |
HP | 0.042132934 | 0.183109776 | -0.308065724 |
HSPA1A | 0.004759711 | 0.083173107 | 14.06455366 |
HSPA1B | 0.000401624 | 0.029719004 | 43.51067573 |
HSPA5 | 0.049211919 | 0.199215907 | -4.000952188 |
HSPG2 | 0.037108807 | 0.170688032 | -0.799766675 |
HYOU1 | 0.046797503 | 0.193488639 | -1.755333501 |
ID1 | 0.049176285 | 0.199199188 | -21.87012489 |
IGF1 | 0.012268804 | 0.117320733 | -1.985869183 |
IGF1R | 0.044759651 | 0.189023721 | -0.284788469 |
IGFBP3 | 0.004793415 | 0.083173107 | -8.807922517 |
IGFBP5 | 0.015115856 | 0.124565943 | -76.96588349 |
IGFBP7 | 0.015026006 | 0.124314131 | -145.1188351 |
ILK | 0.030590933 | 0.155548968 | -10.7781663 |
IRAK1 | 6.00E-07 | 0.000457816 | -6.949457911 |
IRS2 | 0.024361814 | 0.143105038 | -20.96176779 |
JAZF1 | 0.046879476 | 0.193664245 | -0.555380243 |
KCNJ11 | 0.00558881 | 0.088585632 | 2.726401214 |
LEP | 0.028040873 | 0.150582779 | -57.41079874 |
LMNA | 0.006513518 | 0.094072105 | -18.48207326 |
MAPK7 | 0.006553146 | 0.094333607 | -1.093477053 |
MBL2 | 0.012425656 | 0.117889729 | 0.366157191 |
MME | 0.027160116 | 0.148960437 | -6.005801982 |
MMP2 | 0.009525559 | 0.10790344 | -1.025550424 |
MMP9 | 0.019341161 | 0.135128597 | -1.989161057 |
MTHFD1L | 0.049620375 | 0.200063944 | -0.971080414 |
MYH9 | 0.01839393 | 0.133532534 | -115.1098266 |
MYO5C | 0.024974191 | 0.144608898 | -17.57279821 |
NAGLU | 0.010376149 | 0.111370959 | -3.091779874 |
NCALD | 0.017585566 | 0.131219402 | -3.093713541 |
NCF1 | 0.042532611 | 0.1840836 | -0.583569163 |
NGB | 0.027689822 | 0.150017052 | 0.437394974 |
NOS3 | 0.023016716 | 0.141144494 | -6.452918031 |
NOV | 0.020912345 | 0.137659256 | -3.915971617 |
NOX4 | 0.005805931 | 0.089356045 | -1.286637107 |
NPY5R | 0.037655092 | 0.171592912 | -0.491861834 |
NQO1 | 0.012909412 | 0.118882828 | -12.04487457 |
NR1H3 | 0.027873006 | 0.150260352 | -15.31110569 |
PARL | 0.042725121 | 0.18453585 | -7.212281312 |
PC | 0.017718931 | 0.131565107 | -10.40761113 |
PDE5A | 7.43E-06 | 0.002919266 | -2.342429144 |
PDGFB | 0.042020256 | 0.182777943 | -2.014962744 |
PDGFD | 0.00959303 | 0.108003087 | -1.065125924 |
PDGFRB | 0.006952211 | 0.096475834 | -56.95112525 |
PECAM1 | 0.025896076 | 0.146408849 | -43.26737066 |
PIK3CA | 0.014287724 | 0.122266956 | -0.232641235 |
PLEKHH2 | 0.032433069 | 0.159871391 | -2.480357031 |
PLTP | 0.012638001 | 0.118362277 | -8.120788792 |
PMP22 | 0.011434436 | 0.114555003 | -35.78623068 |
POMC | 0.004437748 | 0.08161499 | 0.811993041 |
PON2 | 0.008596664 | 0.103653477 | -20.54835711 |
PON3 | 0.006292684 | 0.092635126 | -1.771294125 |
PPARG | 0.029506327 | 0.153005263 | -21.53287041 |
PPARGC1A | 0.002089065 | 0.062719311 | 15.3952491 |
PRCP | 0.011518631 | 0.114573188 | -23.19121172 |
PRDX2 | 0.038032942 | 0.172378092 | 9.189790523 |
PRDX4 | 0.005801593 | 0.089356045 | -12.9872289 |
PRKAA1 | 0.024317439 | 0.143053898 | -3.052426687 |
PRKCE | 0.027877073 | 0.150260352 | 1.259402261 |
PRMT2 | 0.00673141 | 0.095224379 | -3.891660016 |
PROM1 | 0.044964269 | 0.189428402 | 0.527138557 |
PSMD9 | 0.020462262 | 0.137418878 | -1.01542117 |
PTGER1 | 0.029241707 | 0.152558497 | -0.270989112 |
PTGES | 0.002502167 | 0.066970237 | -3.30542082 |
PTPN1 | 0.044389874 | 0.188204387 | -6.603491916 |
RARRES2 | 0.027752294 | 0.150122546 | -125.7759967 |
RBP4 | 0.025754783 | 0.146111071 | -24.31403995 |
RCAN1 | 1.88E-06 | 0.001077238 | -3.044104984 |
RHOA | 0.019379112 | 0.135128597 | -16.88360126 |
RPS12 | 0.000459095 | 0.030920553 | -193.780074 |
RTN1 | 0.012160421 | 0.116951084 | -2.701825947 |
SAA1 | 0.0357365 | 0.167478464 | -10.66118723 |
SCARB1 | 0.023646228 | 0.142256205 | -34.55467554 |
SERPINB7 | 0.024258489 | 0.143053898 | 0.199760546 |
SGK3 | 0.01548687 | 0.125486039 | -0.920806772 |
SHBG | 0.00498168 | 0.084478621 | -0.379025233 |
SLMAP | 0.008534026 | 0.103373882 | 25.86911206 |
SMAD7 | 0.035609815 | 0.16732437 | -1.6480645 |
SOCS2 | 0.030026864 | 0.154267076 | -5.863396564 |
SOD2 | 0.001660938 | 0.056317443 | 11.24574279 |
SORBS2 | 0.004847934 | 0.083357532 | -1.930475402 |
SPARC | 0.002485679 | 0.066970237 | -128.4030428 |
SPP1 | 0.00179761 | 0.058227429 | -1.231307034 |
SRC | 0.020745109 | 0.13749012 | -0.845200378 |
SREBF1 | 0.004591442 | 0.082344606 | -6.270283946 |
STAT5A | 0.021110555 | 0.138046005 | -40.77357762 |
STEAP4 | 0.01671553 | 0.129128343 | -2.166278514 |
STK11 | 0.029270165 | 0.152655077 | -0.899749931 |
SUCNR1 | 0.005796255 | 0.089356045 | -1.973799837 |
SYVN1 | 0.010739516 | 0.111861558 | -1.782427428 |
TCF7L2 | 0.007884969 | 0.100608076 | -2.380922646 |
TF | 0.022073022 | 0.139451415 | -41.75164076 |
THBS1 | 0.001317416 | 0.050757824 | -17.64969326 |
THBS2 | 8.84E-06 | 0.003223032 | -10.18666084 |
TIMP1 | 0.001127451 | 0.047354843 | -43.7630084 |
TIMP2 | 0.000865117 | 0.042510708 | -51.10772163 |
TIMP3 | 0.013952488 | 0.121254112 | -64.03075474 |
TKT | 0.023949228 | 0.142770703 | -107.2219343 |
TLR2 | 0.037799711 | 0.171827707 | -0.29088146 |
TNFAIP8 | 0.025682519 | 0.146111071 | -3.309234937 |
TNFRSF1B | 0.009162729 | 0.105999618 | -1.54857667 |
TRAF6 | 0.025979227 | 0.146476419 | -0.43582916 |
TRIB3 | 0.016423672 | 0.12837113 | -1.542137986 |
TRPC1 | 0.004595247 | 0.082344606 | -4.022832482 |
TSPO | 0.019776234 | 0.135646723 | -35.76898105 |
TXN | 0.001228173 | 0.049124977 | -32.88669244 |
USF2 | 0.000224041 | 0.021051915 | -5.460475369 |
UTRN | 0.023569884 | 0.142068688 | -3.178664764 |
VEGFA | 1.94E-05 | 0.004781581 | 2.98355458 |
VEGFC | 0.014755934 | 0.123483687 | -5.663182696 |
VIP | 0.01067737 | 0.111743736 | -1.083417234 |
VWF | 0.014409703 | 0.122655909 | -241.5771226 |
WFS1 | 0.016542336 | 0.128612064 | -30.33073398 |
ZEB2 | 0.031672936 | 0.157887734 | -2.921879705 |