| CNDP1 |
| LOCUS ID | 84735 | ||||
| GENE_SYMBOL | CNDP1 | ||||
| GENE NAME | carnosine dipeptidase 1 (metallopeptidase M20 fami | ||||
| SYNONYMNS | CN1 CPGL2 HsT2308 | ||||
| CHROMOSOME | 18 | ||||
| HOMOLOGENE ID | 57178 | ||||
| SOURCE | HUMAN |
| PMIDs | 24756973 |
| GENE SUMMARY |
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| This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region. [provided by RefSeq, Jul 2008] |
| OBSERVATION |
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| 1. Homozygosity for a 5-leucine repeat (5L-5L) in the carnosinase gene (CNDP1) has been associated with a reduced prevalence of diabetic nephropathy in cross-sectional studies in patients with type 2 diabetes, particularly in women. |