A Gene Atlas of Type 2 Diabetes Mellitus Associated Complex Disorders
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FGF21 |
LOCUS ID | 26291 | ||||||
GENE_SYMBOL | FGF21 | ||||||
GENE NAME | fibroblast growth factor 21 | ||||||
SYNONYMNS | |||||||
CHROMOSOME | 19 | ||||||
HOMOLOGENE ID | 10428 | ||||||
SOURCE | HUMAN |
PMIDs | 27839924 |
GENE SUMMARY |
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Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue. [provided by RefSeq, Mar 2016] |
OBSERVATION |
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1. This result suggests that the very low serum FGF21 level itself may associate with diabetic retinopathy and also relatively elevated serum FGF21 level may be a compensatory increase to protect against microvascular injury. |