FGF21
LOCUS ID26291
GENE_SYMBOLFGF21
GENE NAMEfibroblast growth factor 21
SYNONYMNS
CHROMOSOME19
HOMOLOGENE ID10428
SOURCEHUMAN
PMIDs27839924
GENE SUMMARY
Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue. [provided by RefSeq, Mar 2016]

OBSERVATION
1. This result suggests that the very low serum FGF21 level itself may associate with diabetic retinopathy and also relatively elevated serum FGF21 level may be a compensatory increase to protect against microvascular injury.