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FBXL17 |
LOCUS ID | 64839 |
GENE_SYMBOL | FBXL17 |
GENE NAME | F-box and leucine rich repeat protein 17 |
SYNONYMNS | Fbl17,Fbx13,FBXO13 |
CHROMOSOME | 5 |
HOMOLOGENE ID | 79859 |
GENE SUMMARY |
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Members of the F-box protein family, such as FBXL17, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008] |