| FTO |
| LOCUS ID | 79068 |
| GENE_SYMBOL | FTO |
| GENE NAME | fat mass and obesity associated |
| SYNONYMNS | ALKBH9 |
| CHROMOSOME | 16 |
| HOMOLOGENE ID | 8053 |
| GENE SUMMARY |
|---|
| This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygese superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated D and R damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011] |