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GCKR |
LOCUS ID | 2646 |
GENE_SYMBOL | GCKR |
GENE NAME | glucokinase (hexokinase 4) regulator |
SYNONYMNS | GKRP, FGQTL5 |
CHROMOSOME | 2 |
HOMOLOGENE ID | 1139 |
GENE SUMMARY |
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This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an ictive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008] |