GCKR
LOCUS ID2646
GENE_SYMBOLGCKR
GENE NAMEglucokinase (hexokinase 4) regulator
SYNONYMNSGKRP, FGQTL5
CHROMOSOME2
HOMOLOGENE ID1139
GENE SUMMARY
This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an ictive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq, Jul 2008]