GFM1
LOCUS ID85476
GENE_SYMBOLGFM1
GENE NAMEG elongation factor mitochondrial 1
SYNONYMNSEFG,GFM,EFG1,EFGM,EGF1,hEFG1,COXPD1
CHROMOSOME3
HOMOLOGENE ID6449
GENE SUMMARY
Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. [provided by RefSeq, Jul 2008]