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IGF1 |
LOCUS ID | 3479 |
GENE_SYMBOL | IGF1 |
GENE NAME | insulin-like growth factor 1 (somatomedin C) |
SYNONYMNS | MGF, IGFI, IGF-I |
CHROMOSOME | 12 |
HOMOLOGENE ID | 55526 |
GENE SUMMARY |
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The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015] |