| ITGA2 |
| LOCUS ID | 3673 |
| GENE_SYMBOL | ITGA2 |
| GENE NAME | integrin subunit alpha 2 |
| SYNONYMNS | BR, GPIa, CD49B, HPA-5, VLA-2, VLAA2 |
| CHROMOSOME | 5 |
| HOMOLOGENE ID | 1662 |
| GENE SUMMARY |
|---|
| This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neotal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Altertive splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |