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NEUROD1 |
LOCUS ID | 4760 |
GENE_SYMBOL | NEUROD1 |
GENE NAME | neuronal differentiation 1 |
SYNONYMNS | BETA2,BHF-1,MODY6,NEUROD,bHLHa3 |
CHROMOSOME | 2 |
HOMOLOGENE ID | 1871 |
GENE SUMMARY |
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This gene encodes a member of the NeuroD family of basic helix-loop-helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E-box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus. [provided by RefSeq, Jul 2008] |