NOS3
LOCUS ID4846
GENE_SYMBOLNOS3
GENE NAMEnitric oxide synthase 3
SYNONYMNSeNOS, ECNOS
CHROMOSOME7
HOMOLOGENE ID504
GENE SUMMARY
Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]