PON1
LOCUS ID5444
GENE_SYMBOLPON1
GENE NAMEparaoxose 1
SYNONYMNSESA, PON, MVCD5
CHROMOSOME7
HOMOLOGENE ID68058
GENE SUMMARY
The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in corory artery disease. The gene is found in a cluster of three related paraoxose genes at 7q21.3. [provided by RefSeq, Oct 2008]