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TCF7L2 |
LOCUS ID | 6934 |
GENE_SYMBOL | TCF7L2 |
GENE NAME | transcription factor 7-like 2 (T-cell specific, HM |
SYNONYMNS | TCF4, TCF-4 |
CHROMOSOME | 10 |
HOMOLOGENE ID | 7564 |
GENE SUMMARY |
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This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt sigling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010] |