TRPS1
LOCUS ID7227
GENE_SYMBOLTRPS1
GENE NAMEtranscriptional repressor GATA binding 1
SYNONYMNSGC79,LGCR
CHROMOSOME8
HOMOLOGENE ID8556
GENE SUMMARY
This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III. [provided by RefSeq, Jul 2008]