TSPAN8
LOCUS ID7103
GENE_SYMBOLTSPAN8
GENE NAMEtetraspanin 8
SYNONYMNSCO-029,TM4SF3
CHROMOSOME12
HOMOLOGENE ID20968
GENE SUMMARY
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]