| AQP4 |
| LOCUS ID | 361 | ||||
| GENE_SYMBOL | AQP4 | ||||
| GENE NAME | aquaporin 4 | ||||
| SYNONYMNS | MIWC, HMIWC2 | ||||
| CHROMOSOME | 18 | ||||
| HOMOLOGENE ID | 37507 | ||||
| SOURCE | RAT |
| PMIDs | 22449442 |
| GENE SUMMARY |
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| This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| OBSERVATION |
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| 1. Therefore, regulation of retinal function by AQP4 may attenuate diabetic retinopathy, offering a promising therapeutic strategy for diabetic retinopathy. |