| ADK |
| LOCUS ID | 132 | ||||||||||
| GENE_SYMBOL | ADK | ||||||||||
| GENE NAME | adenosine kinase | ||||||||||
| SYNONYMNS | AK | ||||||||||
| CHROMOSOME | 10 | ||||||||||
| HOMOLOGENE ID | 4891 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript v |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Retinopathy | 1. Here we demonstrate that AKI-enhanced adenosine signaling provides protection from DR in mice | 23770229 |