| ADM2 |
| LOCUS ID | 79924 | ||||||||||
| GENE_SYMBOL | ADM2 | ||||||||||
| GENE NAME | adrenomedullin 2 | ||||||||||
| SYNONYMNS | AM2 dJ579N16.4 | ||||||||||
| CHROMOSOME | 22 | ||||||||||
| HOMOLOGENE ID | 49801 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes a member of the calcitonin gene-related peptide (CGRP)/calcitonin family of hormones that play a role in the regulation of cardiovascular homeostasis, prolactin release, anti-diuresis, anti-natriuresis, and regulation of food and water intake. The encoded protein is proteolytically processed to generate one or more biologically active peptides. [provided by RefSeq, Jul 2015] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. ADM2 treatment restored the high-fat diet-induced early insulin resistance in adipose tissue, mainly via inhibition of adipocyte MHCII antigen presentation and CD4(+) T-cell activation. | 27207558 |