| AIM2 |
| LOCUS ID | 9447 | ||||||||||
| GENE_SYMBOL | AIM2 | ||||||||||
| GENE NAME | absent in melanoma 2 | ||||||||||
| SYNONYMNS | PYHIN4 | ||||||||||
| CHROMOSOME | 1 | ||||||||||
| HOMOLOGENE ID | 83226 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. Deficiency in AIM2 induces inflammation and adipogenesis in white adipose tissue leading to obesity and insulin resistance. | 31511929 |