| ALCAM |
| LOCUS ID | 214 | ||||||||||
| GENE_SYMBOL | ALCAM | ||||||||||
| GENE NAME | activated leukocyte | ||||||||||
| SYNONYMNS | MEMD, CD166 | ||||||||||
| CHROMOSOME | 3 | ||||||||||
| HOMOLOGENE ID | 1229 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus. [provided by RefSeq, Oct 2008] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. ALCAM a novel biomarker in patients with type 2 diabetes mellitus complicated with diabetic nephropathy. Expression of ALCAM and S100B in kidney histology from patients with DN was determined by immunohistochemistry. | 28325697 |