| ALPL |
| LOCUS ID | 249 | ||||||||||
| GENE_SYMBOL | ALPL | ||||||||||
| GENE NAME | alkaline phosphatase | ||||||||||
| SYNONYMNS | HOPS, TP, APTP, TNSALP, AP-TP | ||||||||||
| CHROMOSOME | 1 | ||||||||||
| HOMOLOGENE ID | 37314 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatasesintestil, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-non |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. Urinary GGT and ALP have potential value in the diagnosis of nephropathy in type 2 diabetic patients, but GGT has a slightly higher ability to discriminate nephropathy than ALP. | 21527256 |