| APOM |
| LOCUS ID | 55937 | ||||||||||
| GENE_SYMBOL | APOM | ||||||||||
| GENE NAME | apolipoprotein M | ||||||||||
| SYNONYMNS | G3a, NG20, apo-M, HSPC336 | ||||||||||
| CHROMOSOME | 6 | ||||||||||
| HOMOLOGENE ID | 10308 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alterte splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Atherosclerosis | 1. apoM expression is reduced in some patients with diabetes and may well have a paradoxical effect on the development and progression of atherosclerosis. | 19909825 |