| AQP2 |
| LOCUS ID | 359 | ||||||||||
| GENE_SYMBOL | AQP2 | ||||||||||
| GENE NAME | aquaporin 2 | ||||||||||
| SYNONYMNS | AQP-CD, WCH-CD | ||||||||||
| CHROMOSOME | 12 | ||||||||||
| HOMOLOGENE ID | 20137 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by Re |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Nephropathy | 1. Taken together, these data suggest a possible use of AQP5 and AQP2 as novel noninvasive biomarkers to help in classifying the clinical stage of DN. DOI: 10.1155/2017/4360357 PMCID: PMC5299189 | 28246612 |