| AQP9 |
| LOCUS ID | 366 | ||||||||||
| GENE_SYMBOL | AQP9 | ||||||||||
| GENE NAME | aquaporin 9 | ||||||||||
| SYNONYMNS | SSC1 AQP-9 T17287 HsT17287 | ||||||||||
| CHROMOSOME | 15 | ||||||||||
| HOMOLOGENE ID | 41405 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| The aquaporins are a family of water-selective membrane channels. This gene encodes a member of a subset of aquaporins called the aquaglyceroporins. This protein allows passage of a broad range of noncharged solutes and also stimulates urea transport and osmotic water permeability. This protein may also facilitate the uptake of glycerol in hepatic tissue . The encoded protein may also play a role in specialized leukocyte functions such as immunological response and bactericidal activity. Alterna |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. Obese patients with T2D showed increased plasma glycerol as well as lower P(gly) and hepatic AQP9 expression. | 24418844 |