| ATF3 |
| LOCUS ID | 467 | ||||||||||
| GENE_SYMBOL | ATF3 | ||||||||||
| GENE NAME | activating transcrip | ||||||||||
| SYNONYMNS | |||||||||||
| CHROMOSOME | 1 | ||||||||||
| HOMOLOGENE ID | 1265 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. Insulin resistance and hepatic steatosis were associated with increased ATF3 expression and decreased fatty acid oxidation . | 28365312 |