| BCO2 |
| LOCUS ID | 83875 | ||||||||||
| GENE_SYMBOL | BCO2 | ||||||||||
| GENE NAME | beta-carotene oxygen | ||||||||||
| SYNONYMNS | BCDO2, B-DIOX-II | ||||||||||
| CHROMOSOME | 11 | ||||||||||
| HOMOLOGENE ID | 12912 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| This gene encodes an enzyme which oxidizes carotenoids such as beta-carotene during the biosynthesis of vitamin A. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Cardiovascular | 1. Mutation in intron 2 of BCO2 gene is also supposed to be related to the expression of IL-18, a pro-inflammatory cytokine associated with obesity, cardiovascular diseases, and type 2 diabetes. | 27390265 |