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BMP2 |
LOCUS ID | 650 | ||||||||||
GENE_SYMBOL | BMP2 | ||||||||||
GENE NAME | bone morphogenetic p | ||||||||||
SYNONYMNS | BDA2, BMP2A | ||||||||||
CHROMOSOME | 20 | ||||||||||
HOMOLOGENE ID | 926 |
microRNAs | NA | NA |
GENE SUMMARY |
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This gene encodes a member of the transforming growth factor-beta (TGFB) superfamily. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which induces bone and cartilage formation. [provided by RefSeq, Nov 2015] |
OBSERVATIONS |
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Complication | Evidence | PMID |
Atherosclerosis | 1. Increased plasma BMP-2 levels are associated with atherosclerosis burden and corory calcification in type 2 diabetic patients. | 26003174 |