| C1QBP |
| LOCUS ID | 708 | ||||||||||
| GENE_SYMBOL | C1QBP | ||||||||||
| GENE NAME | complement C1q bindi | ||||||||||
| SYNONYMNS | p32, HABP1, gC1qR, GC1QBP, SF2p32, gC1Q-R, COXPD33, SF2AP32 | ||||||||||
| CHROMOSOME | 17 | ||||||||||
| HOMOLOGENE ID | 31023 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein. |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Neuropathy | 1. We identified four genes differentially expressed between the two study arms post-treatment, but not pre-treatment: GFRA2 (GDNF family receptor alpha-2), C1QBP (complement C1q binding protein), RAB35 (member of RAS oncogene family) and SYNJ1 (synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1). | 30221321 |