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CCL19 |
LOCUS ID | 6363 | ||||||||||
GENE_SYMBOL | CCL19 | ||||||||||
GENE NAME | C-C motif chemokine | ||||||||||
SYNONYMNS | ELC CKb11 MIP3B MIP-3b SCYA19 | ||||||||||
CHROMOSOME | 9 | ||||||||||
HOMOLOGENE ID | 4569 |
microRNAs | NA | NA |
GENE SUMMARY |
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This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organ |
OBSERVATIONS |
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Complication | Evidence | PMID |
Insulin resistance and inflammation | 1. Our data indicate that besides CCL2 and CCL5, numerous other chemokines such as CCL19 are expressed by adipocytes under obesity-associated chronic inflammation. | 23824685 |