| CCL4 |
| LOCUS ID | 6351 | ||||||||||
| GENE_SYMBOL | CCL4 | ||||||||||
| GENE NAME | C-C motif chemokine | ||||||||||
| SYNONYMNS | ACT2 G-26 HC21 LAG1 LAG-1 MIP1B SCYA2 SCYA4 MIP1B1 AT744.1 MIP-1-beta | ||||||||||
| CHROMOSOME | 17 | ||||||||||
| HOMOLOGENE ID | 48153 |
| microRNAs | NA | NA |
| GENE SUMMARY |
|---|
| The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. [provided by RefSeq, Dec 2012] |
| OBSERVATIONS |
|---|
| Complication | Evidence | PMID |
| Insulin resistance and inflammation | 1. Palmitate Activates CCL4 Expression in Human Monocytic Cells via TLR4/MyD88 Dependent Activation of NF-kB/MAPK/ PI3K Signaling Systems. | 29669317 |