| CD160 |
| LOCUS ID | 11126 | ||||||||||
| GENE_SYMBOL | CD160 | ||||||||||
| GENE NAME | CD160 molecule | ||||||||||
| SYNONYMNS | NK1, BY55, NK28 | ||||||||||
| CHROMOSOME | 1 | ||||||||||
| HOMOLOGENE ID | 5122 |
| microRNAs | NA | NA |
| GENE SUMMARY |
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| CD160 is an 27 kDa glycoprotein which was initially identified with the monoclol antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cD sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. R blot analysis r |
| OBSERVATIONS |
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| Complication | Evidence | PMID |
| Retinopathy | 1. Approximately 48 and 61 spots were identified in control and diabetic retinopathy respectively, of which three protein spots RBP1 (retinol-binding protein 1), NUD10 (Diphosphoinositol polyphosphohydrolase 3 alpha), NGB (neuroglobin) were down regulated and HBG2 (hemoglobin) and BY55 (CD 160 antigen) were upregulated in diabetic retinopathy. | 26129748 |